Pancytopenia responding to treatment of hyperthyro...[Clin Lab Haematol. 2002]

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1: Clin Lab Haematol. 2002 Dec;24(6):385-7. Links

Pancytopenia responding to treatment of hyperthyroidism: a clinical case and review of the literature.

Shaw B, Mehta AB.

Department of Haematology, Royal Free Hospital, London, UK.

A 46-year-old-man received high dose chemotherapy and an autologous stem-cell transplant for multiple plasmacytoma. He had a prolonged period of pancytopenia post-transplantation, which was thought to be due to a suboptimal dose of transplanted stem cells in combination with the effects of interferon therapy and an altered bone marrow microenvironment. Twenty-eight months after the transplant he was found to be hyperthyroid. Anti-thyroid therapy has led to a sustained improvement in his pancytopenia.

PMID: 12452820 [PubMed - indexed for MEDLINE]

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