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Am J Hematol. 2002 Dec;71(4):328-30.

Factor XIII deficiency mistaken for battered child syndrome: case of "correct" test ordering negated by a commonly accepted qualitative test with limited negative predictive value.

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  • 1Department of Pathology, University of California, Irvine, Orange, USA. rsnewman@uci.edu

Abstract

We report herein a case of Factor XIII deficiency that remained undiagnosed until 2 years of age. Part of the delay in diagnosis was a consequence of testing that was performed on a blood sample obtained after plasma transfusion therapy for a life-threatening bleeding episode. Due to insufficient family follow-up after discharge from the hospital, the diagnosis was delayed 1 year until the child was rehospitalized and a pre-transfusion plasma sample was tested. The commonly accepted approach of using only a qualitative test for the diagnosis of factor XIII deficiency is challenged by this case report.

Copyright 2002 Wiley-Liss, Inc.

PMID:
12447966
[PubMed - indexed for MEDLINE]
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