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    Br J Ophthalmol. 2002 Dec;86(12):1390-4.

    Interobserver and intraobserver variability of measurements of uveal melanomas using standardised echography.

    Haritoglou C, Neubauer AS, Herzum H, Freeman WR, Mueller AJ.

    Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany. Christos.Haritoglou@ak-i.med.uni-muenchen.de

    AIMS: To report on the intraindividual and interindividual variability of tumour size (height and base diameter) measurements using standardised echography in a masked prospective study. METHODS: 20 consecutive eyes of 20 patients were examined on four different visits by three experienced examiners using standardised echography. As common in standardised echography, tumour height was evaluated with A-scan technique, while transverse and longitudinal base diameter were calculated with B-scan. RESULTS: Tumour height measurements using A-scan were more accurate than base diameter measurements using B-scan. The standard deviation for tumour height over all visits/measurements was 0.18 mm (A-scan), 0.79 mm for transverse, and 0.69 mm for longitudinal base diameters (B-scan). The interclass correlation coefficient (ICC) was much higher for tumour height measurements with A-scan (0.7735 for three examiners on one visit) than for transverse (0.6563) or longitudinal (0.4522) base diameter measurements with B-scan techniques. CONCLUSIONS: A-scan techniques for tumour height measurements provide very reproducible results with little intraindividual and interobserver variability. As B-scan techniques for tumour base evaluation are less accurate they should be used for topographic and morphological examinations.

    PMID: 12446372 [PubMed - indexed for MEDLINE]

    PMCID: 1771401

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