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Vision Res. 2002 Oct;42(22):2555-9.

Undercorrection of myopia enhances rather than inhibits myopia progression.

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  • 1Department of Optometry, National University of Malaysia, 50300, Kuala Lumpur, Malaysia.

Abstract

The effect of myopic defocus on myopia progression was assessed in a two-year prospective study on 94 myopes aged 9-14 years, randomly allocated to an undercorrected group or a fully corrected control group. The 47 experimental subjects were blurred by approximately +0.75 D (blurring VA to 6/12), while the controls were fully corrected. Undercorrection produced more rapid myopia progression and axial elongation (ANOVA, F(1,374)=14.32, p<0.01). Contrary to animal studies, myopic defocus speeds up myopia development in already myopic humans. Myopia could be caused by a failure to detect the direction of defocus rather than by a mechanism exhibiting a zero-point error.

PMID:
12445849
[PubMed - indexed for MEDLINE]

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