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    Glycoconj J. 2001 Oct;18(10):745-9.

    Agrocybe cylindracea lectin is a member of the galectin family.

    Source

    Department of Biochemical Science and Technology, Faculty of Agriculture, Kagoshima University, 1-21-24 Korimoto Kagoshima 890-0065, Japan. fyagi@chem.agri.kagoshima-u.ac.jp

    Abstract

    The complete amino acid sequence of Agrocybe cylindracea lectin was determined from the peptides obtained by chemical cleavages and enzymatic hydrolyses. The sequence shows 19.1% and 36.8% identity with those of human galectin-1 and Coprinus lectin-1, a fungal galectin, respectively. Seven residues, which are commonly found in carbohydrate recognizing domain (CRD) of galectins, were conserved. However, several insertions in the sequence, compared with those of human galectin-1 and Coprinus lectin-1, suggest that beta-strands S2, F3, and S4 and the loop structures between beta-strands F2 & S3 and F5 & S2 are different from those of galectins reported so far.

    PMID:
    12441663
    [PubMed - indexed for MEDLINE]

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