Prediction of novel archaeal enzymes from sequence...[Protein Sci. 2002]

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1: Protein Sci. 2002 Dec;11(12):2894-8. Links

Prediction of novel archaeal enzymes from sequence-derived features.

Jensen LJ, Skovgaard M, Brunak S.

Center for Biological Sequence Analysis, BioCentrum-DTU, The Technical University of Denmark, DK-2800 Lyngby, Denmark.

The completely sequenced archaeal genomes potentially encode, among their many functionally uncharacterized genes, novel enzymes of biotechnological interest. We have developed a prediction method for detection and classification of enzymes from sequence alone (available at http://www.cbs.dtu.dk/services/ArchaeaFun/). The method does not make use of sequence similarity; rather, it relies on predicted protein features like cotranslational and posttranslational modifications, secondary structure, and simple physical/chemical properties.

PMID: 12441387 [PubMed - indexed for MEDLINE]

PMCID: PMC2373754

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Prediction of novel archaeal enzymes from sequence-derived features.

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