The discovery of novel neuropeptides takes flight. [Genome Biol. 2002]

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1: Genome Biol. 2002 Oct 28;3(11):reviews1032. Epub 2002 Oct 28. Links

The discovery of novel neuropeptides takes flight.

Nichols R.

Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109-0606, USA. nicholsr@umich.edu

Structural data are critical for the elucidation of how peptides are synthesized and how they function. Two recent studies have used nanoscale chromatography together with mass spectrometry to determine the structures of novel neuropeptides in rat and Drosophila. The results shed light on neuropeptide synthesis and function(s) in both vertebrates and insects.

PMID: 12429066 [PubMed - indexed for MEDLINE]

PMCID: PMC244922

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