Format

Send to:

Choose Destination
See comment in PubMed Commons below
Genome Biol. 2002 Oct 23;3(11):reviews0008. Epub 2002 Oct 23.

Finding signals that regulate alternative splicing in the post-genomic era.

Author information

  • 1Department of Pathology, Baylor College of Medicine, Houston, TX 77030, USA. tcooper@bcm.tmc.edu

Abstract

Alternative splicing of pre-mRNAs is central to the generation of diversity from the relatively small number of genes in metazoan genomes. Auxiliary cis elements and trans-acting factors are required for the recognition of constitutive and alternatively spliced exons and their inclusion in pre-mRNA. Here, we discuss the regulatory elements that direct alternative splicing and how genome-wide analyses can aid in their identification.

PMID:
12429065
[PubMed - indexed for MEDLINE]
PMCID:
PMC244920
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for BioMed Central Icon for PubMed Central
    Loading ...
    Write to the Help Desk