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J Neuropsychiatry Clin Neurosci. 2002 Fall;14(4):424-9.

Neuropsychiatric features of frontotemporal dementia: evaluation of consensus criteria and review.

Author information

  • 1Department of Neurology, UCLA School of Medicine, Greater Los Angeles Healthcare System, 11301 Wilshire Boulevard, Los Angeles, CA 90073, USA. mmendez@UCLA.edu

Abstract

Neuropsychiatric features characterize frontotemporal dementia (FTD). The authors evaluated the neuropsychiatric features of 53 FTD patients and retrospectively applied the Consensus Criteria for this disorder. Only one-third of the patients met Consensus Criteria for FTD on presentation. Most had early disengagement with poor insight; however, more than half retained socially appropriate interpersonal conduct and emotional expression. Supportive features, including compulsive-like acts and speech changes, were common presenting features, and 20% developed the Kl├╝ver-Bucy syndrome on 2-year follow-up. Consensus Criteria for FTD offer guidelines for diagnosis, but further refinement is needed, particularly for patients who lack early changes in social interpersonal conduct.

PMID:
12426410
[PubMed - indexed for MEDLINE]
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