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Bioinformatics. 2002 Nov;18(11):1546-7.

QuickTree: building huge Neighbour-Joining trees of protein sequences.

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  • 1The Wellcome Trust Sanger Institute, The Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK. klh@sanger.ac.uk

Abstract

We have written a fast implementation of the popular Neighbor-Joining tree building algorithm. QuickTree allows the reconstruction of phylogenies for very large protein families (including the largest Pfam alignment containing 27000 HIV GP120 glycoprotein sequences) that would be infeasible using other popular methods.

PMID:
12424131
[PubMed - indexed for MEDLINE]
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