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J Virol. 2002 Dec;76(23):12394-8.

Involvement of apolipoprotein E in the hematogenous route of herpes simplex virus type 1 to the central nervous system.

Author information

  • 1Departamento de Biología Molecular and Centro de Biología Molecular Severo Ochoa (C.S.I.C.-U.A.M.), Universidad Autónoma de Madrid, Cantoblanco, 28049 Madrid, Spain.

Abstract

Apolipoprotein E (ApoE), a constituent of the lipoproteins, may be relevant in herpes simplex virus type 1 (HSV-1) infection of the central nervous system (CNS), since HSV-1 binds to human serum ApoE lipoproteins. This study demonstrates the involvement of ApoE in the hematogenous route of HSV-1 to the CNS.

PMID:
12414984
[PubMed - indexed for MEDLINE]
PMCID:
PMC136918
Free PMC Article

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