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J Am Geriatr Soc. 2002 Nov;50(11):1844-6.

Outcome of West Nile fever in older adults.

Author information

  • 1Department of Geriatric Medicine, Sapir Medical Center-Meir Hospital, Affiliated with Tel Aviv University, Sackler Medical School, Kfar-Saba, Israel. ynberner@clalit.org.il

Abstract

OBJECTIVES:

To determine the effect of clinical presentation and cognitive changes on the postdischarge outcome in older adult patients with West Nile fever (WNF).

DESIGN:

Retrospective, cohort analysis.

SETTING:

Meir Hospital located in the center of Israel in the Sharon region.

PARTICIPANTS:

Thirty-two patients aged 65 and older hospitalized during a WNF outbreak.

MEASUREMENTS:

All patients' charts were analyzed retrospectively with special emphasis on their cognitive and functional state. A follow-up examination of patients with functional decline at discharge was performed after 3 months.

RESULTS:

A change in consciousness, rather than in cognition, predicted the outcome. The death rate was 22% (7/32); all fatal cases were aged 78 and older. Similarly, the functional decline and residual damage appeared only in the older age group (>or=75). Eighty-eight percent of the survivors returned to their premorbid function. In contrast to other viral infections, chronic conditions in the subjects had no effect on the outcome.

CONCLUSIONS:

In older adults, WNF carries a high death rate, but the outcome is favorable for the survivors.

PMID:
12410904
[PubMed - indexed for MEDLINE]
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