Effect of Artemisia santonicum L. on blood glucose in normal and alloxan-induced diabetic rabbits

H Korkmaz; A Gürdal

doi:10.1002/ptr.943

Effect of Artemisia santonicum L. on blood glucose in normal and alloxan-induced diabetic rabbits

Phytother Res. 2002 Nov;16(7):675-6. doi: 10.1002/ptr.943.

Authors

H Korkmaz¹, A Gürdal

Affiliation

¹ Department of Chemistry, Faculty of Sciences and Arts Ondokuz Mayis University, Kurupelit, 55139, Samsun, Turkey.

PMID: 12410552
DOI: 10.1002/ptr.943

Abstract

The hypoglycaemic effect of panicles of Artemisia santonicum L. in normal and alloxan-induced diabetic rabbits was investigated. Blood glucose levels were determined after oral administration of an aqueous extract of Artemisia santonicum L. In normal and diabetic rabbits, 2 mL/kg (0.42 g/kg) aqueous extract significantly (p < 0.01) reduced blood glucose levels 6 h after administration, which was consistent and time-dependent.

MeSH terms

Alloxan
Animals
Artemisia*
Blood Glucose / metabolism*
Diabetes Mellitus, Experimental / chemically induced
Diabetes Mellitus, Experimental / drug therapy*
Hypoglycemic Agents / administration & dosage
Hypoglycemic Agents / pharmacology*
Hypoglycemic Agents / therapeutic use
Male
Phytotherapy*
Plant Extracts / administration & dosage
Plant Extracts / pharmacology*
Plant Extracts / therapeutic use
Rabbits / metabolism
Time Factors

Substances

Blood Glucose
Hypoglycemic Agents
Plant Extracts
Alloxan