J Clin Pathol. 2002 Nov;55(11):801-11.

Apoptosis in myocardial ischaemia and infarction.

Krijnen PA, Nijmeijer R, Meijer CJ, Visser CA, Hack CE, Niessen HW.

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Department of Pathology, VU University Medical Centre, PO Box 7075, 1007MB Amsterdam, The Netherlands. paj.krijnen@vumc.nl

Abstract

Recent studies indicate that, in addition to necrosis, apoptosis also plays a role in the process of tissue damage after myocardial infarction, which has pathological and therapeutic implications. This review article will discuss studies in which the role and mechanisms of apoptosis in myocardial infarction were analysed in vivo and in vitro in humans and in animals.

PMID:: 12401816; [PubMed - indexed for MEDLINE]
PMCID:: PMC1769793

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