Department of Radiology, Great Ormond Street Children's Hospital, London, United Kingdom. hallo@gosh.nhs.uk
The last International Classification of Constitutional Disorders of Bone was published in 1998. Since then rapid advances have been made in identifying the molecular changes responsible for defined conditions and new disorders are constantly being delineated. For these reasons a further update on the classification is appropriate. It has been expended to not only the osteochondrodysplasias (33 groups) but also genetically determined dysostoses (3 groups). Copyright 2002 Wiley-Liss, Inc.