Isolated orofacial dyskinesia: a methylphenidate-induced movement disorder

Pediatr Neurol. 2002 Sep;27(3):224-6. doi: 10.1016/s0887-8994(02)00429-0.

Abstract

We report a case of orofacial dyskinesia in a 6-year-old female with attention-deficit-hyperactivity disorder who received a low dose of methylphenidate. The orofacial dyskinesia appeared immediately and subsided rapidly on the same day in an "on-off" fashion and on 3 separate days when methylphenidate was taken. To our knowledge this particular side effect has not been described previously and might represent an unusual type of brain response or sensitivity.

Publication types

  • Case Reports

MeSH terms

  • Attention Deficit Disorder with Hyperactivity / drug therapy*
  • Central Nervous System Stimulants / adverse effects*
  • Central Nervous System Stimulants / therapeutic use
  • Child
  • Dose-Response Relationship, Drug
  • Dyskinesia, Drug-Induced / diagnosis
  • Dyskinesia, Drug-Induced / etiology*
  • Female
  • Humans
  • Methylphenidate / adverse effects*
  • Methylphenidate / therapeutic use
  • Neurologic Examination / drug effects

Substances

  • Central Nervous System Stimulants
  • Methylphenidate