Format

Send to

Choose Destination
See comment in PubMed Commons below
Otolaryngol Clin North Am. 2002 Apr;35(2):275-85.

Nonsyndromic hereditary hearing loss.

Author information

  • 1Section on Hereditary Diseases of the Ear, Department of Cell and Molecular Biology, House Ear Institute, 2100 West Third Street, Los Angeles, CA 90057, USA.

Abstract

Like many areas of medicine, the rapid advances in genetics and molecular biology are revolutionizing our understanding of hearing and balance disorders. Dramatic progress has been made in identifying deafness genes in the past few years. These genes encode proteins of diverse function, including transcription factors, cytoskeletal and extracellular matrix components, and ion channels. The diversity of the genes so far identified is testimony to the complexities of auditory development and function and the power of genetic approaches. In what is about to become the postgenomic era, the study of the proteins encoded by these genes will advance our understanding of auditory development and function and lead to innovative approaches toward the treatment of patients with hearing disorders.

PMID:
12391618
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk