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J Epidemiol Community Health. 2002 Nov;56(11):843-50.

Measuring the health burden of chronic disease and injury using health adjusted life expectancy and the Health Utilities Index.

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  • 1Institute for Clinical Evaluative Sciences, Toronto, Canada. d.manuel@utoronto.ca



To estimate the burden of illness from chronic disease and injury using a population based health survey, which contains both measures of chronic disease and a utility based health related quality of life (HRQOL) measure.


An adapted Sullivan method was used to calculate cause deleted health adjusted life expectancies for chronic conditions.


Ontario, Canada, 1996/97.


The 1996/97 Ontario Health Survey (n=35 527) was used to estimate the prevalence of chronic conditions. A cause deleted approach was used to estimate the impact of these conditions on the Health Utilities Index (HUI). Cause deleted probabilities of dying were derived with the cause eliminated life table technique and death data from vital statistics for Ontario 1996/97 (n=156 610).


Eliminating cardiovascular disease and cancer will cause an "expansion of morbidity", while eliminating mental conditions and musculosketal disorders will result in a "contraction of morbidity". The HUI score varies depending on chronic condition, age, and sex-most of which were assumed not to vary in previous summary measures of population health.


Health adjusted life expectancy estimated for chronic conditions using a utility based measure of health related quality of life from population health surveys addresses several limitations of previous studies that estimate the burden of disease using either a categorical measure of disability or expert opinion and related epidemiological evidence.

[PubMed - indexed for MEDLINE]
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