Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Microsc Res Tech. 2002 Oct 15;59(2):109-18.

Image analysis and morphometry in the diagnosis of breast cancer.

Author information

  • 1Department of Pathology, Mount Sinai School of Medicine, New York, New York 10029, USA. Joan.Gil@mssm.edu

Abstract

Image Analysis, a complicated field still in the early stages of application to Pathology, has the capability of rendering major contributions to the diagnosis, prognosis, and management of malignancies of the breast. The present review summarizes the main problems and the general approach to the use of this technique for quantitating immunohistochemical stain results, obtaining DNA histograms, and making de novo diagnoses in routine materials of the Pathology service. In the case of diagnosis, the main steps are sampling, segmentation, and measures of chromatin texture. Currently, the limiting factor for all routine applications of image analysis is probably the absence of a reliable automatic nuclear segmentation.

Copyright 2002 Wiley-Liss, Inc.

PMID:
12373721
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for John Wiley & Sons, Inc.
    Loading ...
    Write to the Help Desk