Neuron. 2002 Aug 29;35(5):827-41.

Making connections in the fly visual system.

Source

Department of Biological Chemistry, Howard Hughes Medical Institute, University of California, School of Medicine, Los Angeles, CA 90095, USA.

Abstract

Understanding the molecular mechanisms that regulate formation of precise patterns of neuronal connections within the central nervous system remains a challenging problem in neurobiology. Genetic studies in worms and flies and molecular studies in vertebrate systems have led to an increasingly sophisticated understanding of how growth cones navigate toward their targets and form topographic maps. Considerably less is known about how growth cones recognize their cellular targets and form synapses with them. Here, we review connection formation in the fly visual system, the methodological approaches used to study it, and recent progress in uncovering the molecular basis of connection specificity.

PMID:: 12372279; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Review

MeSH Terms

Substances

Cadherins

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Supplemental Content

Save items

Related citations in PubMed

Neuronal cooperativity in the visual system of the fly. [Acta Biochim Biophys Acad Sci ...]
Neuronal cooperativity in the visual system of the fly.
Reichardt W. Acta Biochim Biophys Acad Sci Hung. 1977; 12(2):99-120.
Adaptation of velocity encoding in synaptically coupled neurons in the fly visual system. [J Neurosci. 2008]
Adaptation of velocity encoding in synaptically coupled neurons in the fly visual system.
Kalb J, Egelhaaf M, Kurtz R. J Neurosci. 2008 Sep 10; 28(37):9183-93.
Review Wiring of the brain by a range of guidance cues. [Prog Neurobiol. 2002]
Review Wiring of the brain by a range of guidance cues.
Yamamoto N, Tamada A, Murakami F. Prog Neurobiol. 2002 Dec; 68(6):393-407.
Review Key roles of Ephs and ephrins in retinotectal topographic map formation. [Brain Res Bull. 2009]
Review Key roles of Ephs and ephrins in retinotectal topographic map formation.
Scicolone G, Ortalli AL, Carri NG. Brain Res Bull. 2009 Jun 30; 79(5):227-47. Epub 2009 Apr 1.
Review Synapse formation in developing neural circuits. [Curr Top Dev Biol. 2009]
Review Synapse formation in developing neural circuits.
Colón-Ramos DA. Curr Top Dev Biol. 2009; 87:53-79.

See reviews... See all...

Cited by 29 PubMed Central articles

Comparative analysis of Neph gene expression in mouse and chicken development. [Histochem Cell Biol. 2012]
Comparative analysis of Neph gene expression in mouse and chicken development.
Völker LA, Petry M, Abdelsabour-Khalaf M, Schweizer H, Yusuf F, Busch T, Schermer B, Benzing T, Brand-Saberi B, Kretz O, et al. Histochem Cell Biol. 2012 Mar; 137(3):355-66. Epub 2011 Dec 29.
Membrane-targeted WAVE mediates photoreceptor axon targeting in the absence of the WAVE complex in Drosophila. [Mol Biol Cell. 2011]
Membrane-targeted WAVE mediates photoreceptor axon targeting in the absence of the WAVE complex in Drosophila.
Stephan R, Gohl C, Fleige A, Klämbt C, Bogdan S. Mol Biol Cell. 2011 Nov; 22(21):4079-92. Epub 2011 Sep 7.
Guidance receptor degradation is required for neuronal connectivity in the Drosophila nervous system. [PLoS Biol. 2010]
Guidance receptor degradation is required for neuronal connectivity in the Drosophila nervous system.
Williamson WR, Yang T, Terman JR, Hiesinger PR. PLoS Biol. 2010 Dec 7; 8(12):e1000553. Epub 2010 Dec 7.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Making connections in the fly visual system.
Making connections in the fly visual system.
Neuron. 2002 Aug 29 ;35(5):827-41.

PubMed
Socio-economic differences in fruit and vegetable consumption among Australian a...
Socio-economic differences in fruit and vegetable consumption among Australian adolescents and adults.
Public Health Nutr. 2002 Oct ;5(5):663-9.

PubMed
Mining microarray expression data by literature profiling.
Mining microarray expression data by literature profiling.
Genome Biol. 2002 Sep 13 ;3(10):RESEARCH0055. Epub 2002 Sep 13 .

PubMed
Airway obstruction induced by inhaled acetaldehyde in asthma: repeatability rela...
Airway obstruction induced by inhaled acetaldehyde in asthma: repeatability relationship to adenosine 5'-monophosphate responsiveness.
J Investig Allergol Clin Immunol. 2002 ;12(2):91-8.

PubMed
Prevalence of latex sensitization in health care workers of a general hospital i...
Prevalence of latex sensitization in health care workers of a general hospital in Palermo, Sicily.
J Investig Allergol Clin Immunol. 2002 ;12(2):114-9.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: