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Max Planck Institute for Biochemistry, Am Klopferspitz 18a, 82152 Martinsried, Germany.
A paper in the August 9 issue of Cell describes a novel role for the nucleoporin Npap60/Nup50 as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. These findings add a new dimension of complexity to the current understanding of protein transport pathways.
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