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Epilepsy Res. 2002 Sep;51(1-2):13-21.

Nonconvulsive status epilepticus with frontal features: quantitating severity of subclinical epileptiform discharges provides a marker for treatment efficacy, recurrence and outcome.

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  • 1Department of Neurology, VA Greater Los Angeles Healthcare System, Sepulveda Ambulatory Care Center and Nursing Home Care Unit, 16111 Plummer Street, Sepulveda, CA 91343, USA. eliotlicht@earthlink.net

Abstract

Nonconvulsive status epilepticus (NCSE) is difficult to diagnose but is an important cause of cognitive impairment. Electroencephalogram (EEG) monitoring is required for diagnosis and treatment. Little is known regarding the stability of subclinical epileptiform discharges (SEDs) preceding NCSE nor what strategies may optimize patient outcomes. We report extended follow-up of patients with recurrent frontal SEDs, integrating EEG and cognitive findings before and following treatment of NCSE, and show that quantitating SED severity provides an objective marker of treatment efficacy and recurrence.

Copyright 2002 Elsevier Science B.V.

PMID:
12350380
[PubMed - indexed for MEDLINE]
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