Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Neurology. 2002 Sep 24;59(6):954-5.

Therapy-related acute myeloblastic leukemia after mitoxantrone treatment in a patient with MS.

Author information

  • 1Department of Neurology, Hôpital Purpan, Toulouse University Medical Center, Toulouse, France. dbrassat@yahoo.fr

Abstract

The authors report a patient with severe secondary progressive MS who responded to mitoxantrone but developed a fatal acute myeloblastic leukemia 15 months after completion of mitoxantrone therapy. Therapy-related acute leukemia (TRAL) in relation with mitoxantrone is rare; this patient was the first case among a cohort of 802 French MS patients treated with mitoxantrone. Nevertheless, this case stresses the need to further evaluate the long-term risk of TRAL in patients with MS who receive mitoxantrone.

Comment in

PMID:
12297591
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for HighWire
    Loading ...
    Write to the Help Desk