Send to

Choose Destination
See comment in PubMed Commons below
Brief Bioinform. 2002 Sep;3(3):236-45.

HMM-based databases in InterPro.

Author information

  • 1Pfam Group, The Wellcome Trust Sanger Institute, Hinxton, UK.


Protein family databases are an important resource for protein annotation and understanding protein evolution and function. In recent years hidden Markov models (HMMs) have become one of the key technologies used for detection of members of these families. This paper reviews the Pfam, TIGRFAMs and SMART databases that use the profile-HMMs provided by the HMMER package.

[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Write to the Help Desk