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Phytother Res. 2002 Aug;16(5):488-90.

Effect of Ginkgo biloba extract on beta-adrenergic receptors in different rat brain regions.

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  • 1Department of Chemistry and Biochemistry, Faculty of Ecology, University of Forestry, 10 Kliment Ohridski Avenue, Sofia 1756, Bulgaria.


The effect of oral administration of Ginkgo biloba extract at a dose of 90 mg/kg for 7 consecutive days on rat brain beta-adrenergic receptors in the frontal cortex, hippocampus, striatum and hypothalamus was studied. Ginkgo biloba treatment induced a significant decrease in the density (B(max)) of beta-adrenoreceptors in the frontal cortex and hippocampus. It has been suggested that modulation of the beta-adrenergic system is implicated in the favourable effects of Ginkgo biloba extracts on learning and memory.

Copyright 2002 John Wiley & Sons, Ltd.

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