Abstract
We report 3 patients referred to the bone clinic after spinal fractures. Dual energy X-ray absorptiometry showed severe osteoporosis. Each patient was found to have a history of prostatic carcinoma and long-term treatment with goserelin. We suggest that all patients who have received androgen deprivation therapy for more than 1 year should be evaluated by bone densitometry.
MeSH terms
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Aged
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Aged, 80 and over
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Antineoplastic Agents, Hormonal / administration & dosage
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Antineoplastic Agents, Hormonal / adverse effects*
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Carcinoma / drug therapy*
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Carcinoma / pathology
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Densitometry
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Femoral Fractures / diagnosis
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Femoral Fractures / etiology
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Follow-Up Studies
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Fractures, Spontaneous / diagnosis
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Fractures, Spontaneous / etiology*
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Goserelin / administration & dosage
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Goserelin / adverse effects*
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Humans
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Male
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Osteoporosis / chemically induced*
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Osteoporosis / complications
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Osteoporosis / diagnosis
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Prostatic Neoplasms / drug therapy*
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Prostatic Neoplasms / pathology
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Risk Assessment
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Severity of Illness Index
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Spinal Fractures / diagnosis
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Spinal Fractures / etiology
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Thoracic Vertebrae / injuries
Substances
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Antineoplastic Agents, Hormonal
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Goserelin