Display Settings:


Send to:

Choose Destination
See comment in PubMed Commons below
Curr Opin Genet Dev. 2002 Oct;12(5):592-600.

Molecular mechanisms of selector gene function and evolution.

Author information

  • 1Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York 10032, USA. rsm10@columbia.edu


Selector proteins regulate the formation and identity of animal body regions, organs, tissues, and cell types. Recent studies have focused on the regulation of the DNA binding and transcriptional regulatory activity of this special class of transcription factors. Elucidation of the architecture of selector-regulated target gene enhancers and gene networks, and comparative studies of selector protein function are providing important insights into the evolution of development and morphology.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk