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    J Antibiot (Tokyo). 2002 Jun;55(6):565-70.

    Arylomycins A and B, new biaryl-bridged lipopeptide antibiotics produced by Streptomyces sp. Tü 6075. I. Taxonomy, fermentation, isolation and biological activities.

    Schimana J, Gebhardt K, Höltzel A, Schmid DG, Süssmuth R, Müller J, Pukall R, Fiedler HP.

    Source

    Mikrobiologisches Institut, Universität Tübingen, Auf der Morgenstelle 28, D-72076 Tübingen, Germany.

    Abstract

    New lipopeptide antibiotics, colourless arylomycins A series and yellow arylomycins B series were detected in the culture filtrate and mycelium extracts of Streptomyces sp. Tü 6075 by HPLC-diode-array and HPLC-electrospray-mass-spectrometry screening. Arylomycins are a family of lipohexapeptide antibiotics, which represent the first examples of biaryl-bridged lipopeptides. They show antibiotic activities against Gram-positive bacteria.

    PMID:
    12195962
    [PubMed - indexed for MEDLINE]
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