J Child Adolesc Psychopharmacol. 2002 Summer;12(2):165-71.

Case series: Adderall augmentation of serotonin reuptake inhibitors in childhood-onset obsessive compulsive disorder.

Owley T, Owley S, Leventhal B, Cook EH Jr.

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Section of Child and Adolescent Psychiatry, Department of Psychiatry, University of Chicago, Illinois 60637, USA. towley@yoda.bsd.uchicago.edu

Abstract

Current pharmacological treatment of obsessive compulsive disorder involves the use of selective serotonin reuptake inhibitors (SSRIs). However, a large proportion of patients does not respond fully to these medications despite receiving optimal doses and concomitant cognitive-behavioral therapy. Finding efficacious augmentation strategies has become an important goal of researchers and clinicians working with this population. In this case series, we describe four patients with childhood-onset obsessive compulsive disorder, and with partial or no response to SSRI treatment, who subsequently had a reduction of their symptoms with Adderall augmentation.

PMID:: 12188985; [PubMed - indexed for MEDLINE]

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