Humangenetik. 1975 Dec 23;30(4):317-23.

Sister chromatid exchanges and chromatid interchanges in bloom's syndrome.

Abstract

A comparison is made between the incidences of sister chromatid exchanges (SCE) per chromosome and group of chromosomes and breakage, visible at metaphase like open gaps, breaks, and breaks involved in chromatid interchange formation (CI) in Bloom's syndrome. It can be shown that the two levels of breakage SCE and CI are not correlated as to the locations. The discussion deals with possible interpretations of preferential breakage and reunion at certain homologous chromosomes and the difficulties today to understand SCEs.

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A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes. [Proc Natl Acad Sci U S A. 1974]
A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes.
Chaganti RS, Schonberg S, German J. Proc Natl Acad Sci U S A. 1974 Nov; 71(11):4508-12.
The relationship between sister chromatid exchanges and chromosome aberrations in Bloom's syndrome. [Cytogenet Cell Genet. 1977]
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Review Cytogenetics of Bloom's syndrome.
Kuhn EM, Therman E. Cancer Genet Cytogenet. 1986 May; 22(1):1-18.
Review Sister chromatid exchange (SCE) and structural chromosome aberration in mutagenicity testing. [Hum Genet. 1981]
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Sister chromatid exchanges and chromatid interchanges in bloom's syndrome.

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