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Genome Biol. 2002 Jul 30;3(8):REVIEWS1023. Epub 2002 Jul 30.

Can mammalian cloning combined with embryonic stem cell technologies be used to treat human diseases?

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  • 1Department of Genetics and Development, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA.


Cloning is commonly perceived as a means of generating genetically identical individuals, but it can also be used to obtain genetically matched embryo-derived stem cells, which could potentially be used in the treatment of patients. A recent report offers the first 'proof of principle' of such cloning for therapeutic purposes, referred to as nuclear transplantation to produce stem cells for autologous transplantation.

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