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    Genome Biol. 2002 Jun 18;3(7):REVIEWS1019. Epub 2002 Jun 18.

    Oxidative stress responses--what have genome-scale studies taught us?

    Scandalios JG.

    Department of Genetics, North Carolina State University, Raleigh, NC 27695-7614, USA. jgs@unity.ncsu.edu

    Oxidative stress arises from an imbalance between generation and elimination of reactive oxygen species, often leading to cell death. Genomic tools are expanding our understanding of the antioxidant defenses aerobes have evolved and the recently discovered role(s) of reactive oxygen species in signaling.

    PMID: 12184812 [PubMed - indexed for MEDLINE]

    PMCID: 139384

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