Oxidative stress responses--what have genome-scale studies taught us?

Department of Genetics, North Carolina State University, Raleigh, NC 27695-7614, USA. jgs@unity.ncsu.edu

Oxidative stress arises from an imbalance between generation and elimination of reactive oxygen species, often leading to cell death. Genomic tools are expanding our understanding of the antioxidant defenses aerobes have evolved and the recently discovered role(s) of reactive oxygen species in signaling.

PMID: 12184812 [PubMed - indexed for MEDLINE]

PMCID: PMC139384