Observation of intermittency in gene expression on cDNA microarrays.

Departments of Medicine, Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA. peterson@bcm.tmc.edu

We used scaled factorial moments to search for intermittency in the log expression ratios (LERs) for thousands of genes spotted on cDNA microarrays (gene chips). Results indicate varying levels of intermittency in gene expression. The observation of intermittency in the data analyzed provides a complimentary handle on moderately expressed genes, generally not tackled by conventional techniques.

PMID: 12184800 [PubMed - indexed for MEDLINE]