Send to

Choose Destination
See comment in PubMed Commons below
Methods. 2002 Jul;27(3):218-25.

Measurement of glucose consumption using [(18)F]fluorodeoxyglucose.

Author information

  • 1Max-Planck-Institut für Neurologische Forschung, Gleueler Strasse 50, 50931 Köln, Germany.


The [(18)F]fluorodeoxyglucose (FDG) method to measure glucose metabolism quantitatively in humans is reviewed. The assumptions and the mathematical formulation of the underlying autoradiographic Sokoloff model and its adaptation to positron emission tomography (PET) are described. Various implementations to estimate glucose consumption from measured tissue activity with PET are presented. The dependence on the "lumped constant" and on the accuracy of the input function is discussed. Recommendations for the practical application of different procedures for performing FDG studies are given.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk