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1: Biochim Biophys Acta. 2002 Aug 19;1591(1-3):175-9.Click here to read Links

ABCG4: a novel human white family ABC-transporter expressed in the brain and eye.

Oldfield S, Lowry C, Ruddick J, Lightman S.

University Research Centre for Neuroendocrinology, BRI, University of Bristol, Marlborough Street, Bristol BS2 8HW, UK. s.oldfield@bristol.ac.uk

White family transporters are a group of ATP-binding cassette (ABC) proteins that show sequence homology to the Drosophila white gene product. The Drosophila protein is a subunit of heterodimeric transporters of precursors for eye-pigment synthesis. A novel, human member of this family (ABCG4) has been identified. Northern blotting shows that ABCG4 is expressed specifically in the brain and the eye.

PMID: 12183068 [PubMed - indexed for MEDLINE]