Potential applications of DNA microarrays in biodefense-related diagnostics

David A Stenger; Joanne D Andreadis; Gary J Vora; Joseph J Pancrazio

doi:10.1016/s0958-1669(02)00321-x

Potential applications of DNA microarrays in biodefense-related diagnostics

Curr Opin Biotechnol. 2002 Jun;13(3):208-12. doi: 10.1016/s0958-1669(02)00321-x.

Authors

David A Stenger¹, Joanne D Andreadis, Gary J Vora, Joseph J Pancrazio

Affiliation

¹ Center for Bio/Molecular Science and Engineering, Code 6910, Naval Research Laboratory, Washington, DC 20375, USA. dstenger@ccs.nrl.navy.mil

PMID: 12180094
DOI: 10.1016/s0958-1669(02)00321-x

Abstract

Recent years have witnessed a logarithmic growth in the number of applications involving DNA microarrays. Extrapolation of their use for infectious diagnostics and biodefense-related diagnostics seems obvious. Nevertheless, the application of DNA microarrays to biodefense-related diagnostics will depend on solving a set of substantial, yet approachable, technical and logistical problems that encompass diverse topics from amplification efficiency to bioinformatics.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Review

MeSH terms

Bioterrorism*
DNA, Bacterial / classification*
DNA, Bacterial / genetics
DNA, Viral / classification*
DNA, Viral / genetics
Environmental Microbiology
Environmental Monitoring / instrumentation
Environmental Monitoring / methods
Gene Expression Profiling / instrumentation
Humans
Oligonucleotide Array Sequence Analysis / classification
Oligonucleotide Array Sequence Analysis / instrumentation*
Oligonucleotide Array Sequence Analysis / methods
Oligonucleotide Array Sequence Analysis / trends

Substances

DNA, Bacterial
DNA, Viral