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Curr Opin Biotechnol. 2002 Jun;13(3):204-7.

Challenges in applying microarrays to environmental studies.

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  • 1Environmental Sciences Division, Oak Ridge National Laboratory, PO Box 2008, Oak Ridge, TN 37831, USA. zhouj@ornl.gov

Abstract

Although DNA microarray technology has been used successfully to analyze global gene expression in pure cultures, it has not been rigorously tested and evaluated within the context of complex environmental samples. Adapting microarray hybridization for use in environmental studies faces several challenges associated with specificity, sensitivity and quantitation.

PMID:
12180093
[PubMed - indexed for MEDLINE]
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