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Int J Pharm. 2002 Aug 21;242(1-2):307-11.

Mechanical strength of microcapsules made of different wall materials.

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  • 1School of Chemical Engineering, Queen's University Belfast, BT9 5AG, Belfast, UK.

Abstract

The mechanical strength of microcapsules made of three different wall materials, including melamine-formaldehyde resin, urea-formaldehyde resin and gelatin-gum arabic coacervate, were measured by a micromanipulation technique. Single microcapsules were compressed to large deformations or rupture and the force being imposed on them were measured simultaneously. Melamine-formaldehyde and urea-formaldehyde microcapsules showed clear bursting under compression, and their bursting force, deformation at bursting and deformation at a pesudo yield point were determined. Gelatin microcapsules did not show clear bursting under compression, and their mechanical strength was characterized by the force required to cause their deformation to 50%. The mechanical strengths of these three types of microcapsules are compared in this paper.

PMID:
12176269
[PubMed - indexed for MEDLINE]
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