Radiosensitivity in Fanconi's anemia patients. [Radiother Oncol. 2002]

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1: Radiother Oncol. 2002 Mar;62(3):345-7. Links

Comment in:: Radiother Oncol. 2002 Mar;62(3):350-1; author reply 351-2.

Radiosensitivity in Fanconi's anemia patients.

Alter BP.

Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 7020, Rockville, MD 20852, USA.

The risks of radiation therapy in patients with Fanconi's anemia who have cancer are not clear. Possible toxicity was reported in six of 14 patients: 1/1 with vaginal cancer, 4/10 with head and neck or esophageal cancer, and 1/3 with oral cancer following bone marrow transplant.

PMID: 12175566 [PubMed - indexed for MEDLINE]

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Radiosensitivity in Fanconi's anemia patients.

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