Arch Esp Urol. 2002 Jun;55(5):556-9.

[Bladder choriocarcinoma: retrospective analysis of the de-differentiation of a transitional-cell papillary bladder carcinoma. Apropos of a case].

[Article in Spanish]

Fernández Rosado E, Suárez Pascual G, Rodríguez Gómez I, Blanco Díez A, Alvarez Castelo L, Gomez Veiga F, Novas Castro S, González Martín M, Valbuena Rubira L.

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Servicio de Urología, Hospital Universitario Juan Canalejo, La Coruña, España.

Abstract

OBJECTIVE:

To report a case of choriocarcinoma of the bladder during the different periods of its evolution. The anatomopathological study showing dedifferentiation of a transitional cell tumor is presented and the histogenesis of this rare tumor is discussed.

METHODS:

A case of a rapidly progressing transitional cell tumor of the bladder that dedifferentiated into choriocarcinoma is presented. The pathological findings of the first resections of the transitional cell tumor that progressed to choriocarcinoma are presented and the histogenesis is discussed.

RESULTS/CONCLUSIONS:

Choriocarcinoma of the bladder is very rare, highly malignant and carries a poor prognosis. Its origin is widely accepted to be in the dedifferentiation of a transitional cell tumor. The use of immunohistochemistry and the positivity of HCG support the diagnosis.

PMID:: 12174425; [PubMed - indexed for MEDLINE]

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