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Acta Vet Scand. 2002;43(2):63-74.

Monocarboxylate transporters and lactate metabolism in equine athletes: a review.

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  • 1Department of Basic Veterinary Sciences, University of Helsinki, Finland.


Lactate is known as the end product of anaerobic glycolysis, a pathway that is of key importance during high intensity exercise. Instead of being a waste product lactate is now regarded as a valuable substrate that significantly contributes to the energy production of heart, non-contracting muscles and even brain. The recent cloning of monocarboxylate transporters, a conserved protein family that transports lactate through biological membranes, has given a new insight into the role of lactate in whole body metabolism. This paper reviews current literature on lactate and monocarboxylate transporters with special reference to horses.

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