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Many people are considering or have already switched to a regimen without protease inhibitors in hopes of reversing fat redistribution, or lipodystrophy syndrome(s), and/or to lower cholesterol and triglyceride levels that have been associated with using anti-HIV therapy. The studies below suggest that this strategy may be somewhat effective in reducing triglyceride and cholesterol levels. But there is conflicting information on whether it is effective in reversing fat redistribution.
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