PIP: A surveillance center for the detection of human immunodeficiency virus (HIV) infection at the Regional Medical Research Center in Jabalpur, India, has analyzed 2011 serum samples from foreign students and other high-risk groups since its establishment in November 1986. 10 of these samples have been found to be positive for HIV infection by ELISA testing and were subsequently confirmed as positive by the Western blot test. All 10 positive serum samples were from foreign students from African countries. None of these students had any clinical signs of acquired immunodeficiency syndrome (AIDS). None of the 612 Indians from high-risk groups screened through this surveillance system had antibodies to HIV. However, efforts are now underway to screen a larger sample of Indians considered to be at risk of HIV infection, especially prisoners, prostitutes, blood donors, and patients with sexually transmitted diseases.