Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Emerg Infect Dis. 2002 Aug;8(8):843-9.

Worldwide occurrence of Beijing/W strains of Mycobacterium tuberculosis: a systematic review.

Author information

  • 1London School of Hygeine and Tropical Medicine, London WC1E 7HT, UK. judith.glynn@lshtm.ac.uk

Abstract

Strains of the Beijing/W genotype family of Mycobacterium tuberculosis have caused large outbreaks of tuberculosis, sometimes involving multidrug resistance. This genetically highly conserved family of M. tuberculosis strains predominates in some geographic areas. We have conducted a systematic review of the published reports on these strains to determine their worldwide distribution, spread, and association with drug resistance. Sixteen studies reported prevalence of Beijing strains defined by spoligotyping; another 10 used other definitions. Beijing strains were most prevalent in Asia but were found worldwide. Associations with drug resistance varied: in New York, Cuba, Estonia, and Vietnam, Beijing strains were strongly associated with drug resistance, but elsewhere the association was weak or absent. Although few reports have measured trends in prevalence, the ubiquity of the Beijing strains and their frequent association with outbreaks and drug resistance underline their importance.

PMID:
12141971
[PubMed - indexed for MEDLINE]
PMCID:
PMC2732522
Free PMC Article

Images from this publication.See all images (1)Free text

Figure
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for CDC-NCEZID Icon for PubMed Central
    Loading ...
    Write to the Help Desk