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    Antimicrob Agents Chemother. 2002 Aug;46(8):2723-6.

    Hematologic effects of linezolid: summary of clinical experience.

    Gerson SL, Kaplan SL, Bruss JB, Le V, Arellano FM, Hafkin B, Kuter DJ.

    Division of Hematology/Oncology and Ireland Cancer Center, Case Western Reserve University, University Hospitals of Cleveland, 10900 Euclid Avenue, Cleveland, OH 44106-4937, USA. slg5@cwru.edu

    Linezolid has been associated with reversible myelosuppression. Clinical trial data were evaluated for anemia, thrombocytopenia, and neutropenia. Thrombocytopenia and a slight increased risk for anemia were evident at > or =2 weeks of linezolid treatment. Hematologic abnormalities were consistent with mild, reversible, duration-dependent myelosuppression. Appropriate monitoring is warranted with linezolid use.

    PMID: 12121967 [PubMed - indexed for MEDLINE]

    PMCID: PMC127358

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    Patient drug information

    • Linezolid (Zyvox®)

      Linezolid is used to treat infections, including pneumonia, urinary tract infections, and infections of the skin and blood. Linezolid is in a class of antibacterials called oxazolidinones. It works by stopping the growth...