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    Gut. 2002 Aug;51(2):290-5.

    Molecular pathogenesis of iron overload.

    Trinder D, Fox C, Vautier G, Olynyk JK.

    Source

    Department of Medicine and Western Australian Institute for Medical Research, University of Western Australia, Freemantle, Australia.

    Abstract

    Our current understanding of iron absorption under normal conditions is presented, together with an overview of the clinical disorders of iron overload and the molecular processes that contribute to increased iron deposition in iron overload. Recently, a number of new genes involved in iron metabolism have been identified which is allowing the molecular mechanisms of iron absorption to be elucidated.

    PMID:
    12117898
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC1773304
    Free PMC Article

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