Abstract
Question:
A pregnant patient is taking enalapril for primary hypertension. How safe are angiotension-converting enzyme inhibitors (ACEI) during pregnancy?
Answer:
Evidence of whether ACEIs cause problems during the first trimester of pregnancy is reassuring. There is evidence that they cause severe renal and other problems during the second and third trimesters, however. These drugs should be avoided during pregnancy.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Abnormalities, Drug-Induced / etiology*
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Angiotensin-Converting Enzyme Inhibitors / adverse effects*
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Animals
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Enalapril / adverse effects*
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Female
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Humans
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Hypertension / drug therapy*
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Infant, Newborn
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Pregnancy
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Pregnancy Complications, Cardiovascular / drug therapy*
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Pregnancy Trimesters
Substances
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Angiotensin-Converting Enzyme Inhibitors
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Enalapril