Display Settings:

Format

Send to:

Choose Destination
    Rapid Commun Mass Spectrom. 2002;16(13):1273-5.

    Detection of norbolethone, an anabolic steroid never marketed, in athletes' urine.

    Source

    UCLA Olympic Analytical Laboratory, Department of Molecular Pharmacology, University of California, Los Angeles, CA 90025, USA. dcatlin@ucla.edu

    Abstract

    Norbolethone (13-ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-3-one) is a 19-nor anabolic steroid first synthesized in 1966. During the 1960s it was administered to humans in efficacy studies concerned with short stature and underweight conditions. It has never been reported by doping control laboratories. Norbolethone was identified in two urine samples from one athlete by matching the mass spectra and chromatographic retention times with those of a reference standard. The samples also contained at least one likely metabolite. The samples were also unusual because the concentrations of endogenous steroids were exceptionally low. Since norbolethone is not known to be marketed by any pharmaceutical company, a clandestine source of norbolethone may exist.

    Copyright 2002 John Wiley & Sons, Ltd.

    PMID:
    12112254
    [PubMed - indexed for MEDLINE]

      Supplemental Content

      Save items

      loading

      Recent activity

      Your browsing activity is empty.

      Activity recording is turned off.

      Turn recording back on

      See more...
      Write to the Help Desk