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Epileptic Disord. 2002 Jun;4(2):129-33.

Small hypothalamic hamartomas and gelastic seizures.

Author information

  • 1Department of Neurological Sciences, Epilepsy Center, Federico II University, Via Pansini 5, Naples, Italy. sstriano@libero.it

Abstract

PURPOSE:

To describe the clinical history of patients with gelastic seizures (GSs) related to small-size hypothalamic hamartomas (HHs), and to show some of these unusual seizures.

MATERIAL AND METHODS:

Patients with GSs and the MRI finding of HH < 1 cm diameter. Ictal EEG or video EEG are required.

RESULTS:

Three patients, among 6 with GSs and HH, had a small sessile HH. None of them had a history of precocious puberty, nor any relevant cognitive defects. All patients suffered from other seizure types, in addition to GSs. GSs were drug-resistant in all cases.

CONCLUSION:

since small, not easily recognizable HHs may be present in patients with GSs, a careful MRI study of the hypothalamic, infundibular and mammillary bodys areas is mandatory in these cases [published with videosequences].

PMID:
12105075
[PubMed - indexed for MEDLINE]
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